In 1761 Vane was returned for Durham after a contest. He appears in Henry Fox’s list of Members favourable to the peace preliminaries, December 1762, and was classed by Jenkinson in the autumn of 1763 as a Government supporter. Still, on 13 Feb. 1764 he seconded the motion of his brother-in-law Sir William Meredith against general warrants, and voted with the Opposition in the divisions of 15 and 18 Feb., but appears in Jenkinson’s list of dissenting friends; and on 9 Jan. 1765 he was present at the eve of session meeting at George Grenville’s.
As it was accidentally my lot to be the first person to mention the conduct of the East India Company and in consequence to be of that committee that was appointed, I consider it as my special duty to attend that committee to be better informed and to know whether that general idea ... which was spread to the disadvantage of the servants was founded in truth or not. I think these facts are in a manner proved ... If this House stops short, if these reports are to be neglected upon the table, the House are wilfully blind, and shut their eyes against fact.
Vane did not stand again in 1774, nor does he appear to have attempted to re-enter Parliament at any subsequent election.
He died 28 Apr. 1801.
