The Leke family had been prominent in the north Midlands since the fourteenth century and were the greatest landholders in the Scarsdale Hundred of Derbyshire.
Leke succeeded his father as earl of Scarsdale in 1655. At the Restoration he was noted as being one of those willing to delay their entry into the House until given leave to do so by George Monck, later duke of Albemarle.
Scarsdale does not appear to have been active in the elections for the Cavalier Parliament in Nottinghamshire or Derbyshire. The Cavendishes held a commanding interest in both counties, rivalled in Nottinghamshire only by the Byrons, Chaworths and Pierreponts.
Scarsdale attended the 1664 session for approximately 58 per cent of all sitting days. On 21 Apr. he was named to the committee for the gaming bill. Scarsdale’s attendance during the 1664-5 session increased markedly. Present on just under 89 per cent of all sitting days, he was named to six committees in addition to the sessional committees. His attendance declined during the brief session of October 1665, in which he attended just six of its 19 days, but he was named to four committees, including that considering the bill for preventing the importation of foreign cattle. He was summoned for the trial of Thomas Parker, 15th Baron Morley and Monteagle, at the end of April 1666 and found Morley guilty of manslaughter.
His attendance was particularly assiduous during the 1666-7 session when he was present on almost 97 per cent of all sitting days and was named to nine committees. On 29 Oct. his cousin, the former cavalier Sir Francis Leke, was returned for Nottinghamshire (though there is no reason to believe that Scarsdale employed his interest on his cousin’s behalf in the election). On 23 Jan. 1667 Scarsdale entered a dissent to the refusal to grant a right of appeal from the fire court to the king and the House of Lords.
During the 1667-9 session he attended on approximately 68 per cent of all sitting days and was named to 14 committees. His rate of attendance increased once more in the following (1669) session. Taking his seat at its opening on 19 Oct., he attended each of its 36 days and was named to three committees. He demonstrated a similarly high level of attendance in the following session (1670-1), attending approximately 92 per cent of all sitting days and being named to 41 committees.
Scarsdale sold the lease on his London home in Pall Mall to Nell Gwyn in May 1671, reputedly for £2,500.
Scarsdale resumed his seat for the first session of 1673 and was again assiduous in his attendance. Present on 39 of the 41 sitting days, he was named to 11 committees. He returned to the House for the brief second session of 1673, attending each of its four days. The 1674 session also saw a remarkably high level of attendance; he sat on each of the session’s 38 days during which he was named to five committees.
During the first 1675 session he was present on 95 per cent of all sitting days and was again named to five committees. He was then present on each of the 21 days of the second 1675 session, during which he was named to seven committees. On 20 Nov. he voted in favour of addressing the crown for a dissolution of Parliament.
During the long prorogation, Scarsdale joined with James Howard, 3rd earl of Suffolk, and Charles Howard, earl of Carlisle, in petitioning the king to grant letters of incorporation to the Company of the Royal Fishery of England, in which he had invested.
Scarsdale’s heir, Robert Leke was returned for Newark on the interest of his cousin, Sir Francis Leke, at the first Exclusion election in 1679. There is no suggestion that his candidature was in any way supported by Scarsdale.
During the second Exclusion Parliament, despite advancing age, Scarsdale was present for approximately 85 per cent of sitting days. On 15 Nov. 1680 Scarsdale voted in favour of rejecting the exclusion bill, and on 23 Nov. he voted against appointing a committee to consider the state of the kingdom. On 7 Dec. he found William Howard, Viscount Stafford, guilty of treason.
Scarsdale continued to sit in the session until its close on 10 Jan. 1681. He died, without leaving a will, just over two weeks later on 27 Jan. and was buried in the Hunsdon vault at Westminster Abbey. He was succeeded by his heir, Deincourt, as 3rd earl of Scarsdale.
