Although of obscure background, Clarke’s father was pricked as sheriff of Buckinghamshire in 1599 and entertained the queen at Hitcham in 1602. John Chamberlain commented after the event that Sir William ‘pleased nobody, but gave occasion to have his miserliness and vanity spread far and wide’.
Clarke was over 50 by the time he took his place on the county bench in 1625. He was appointed a deputy lieutenant the following year, when he was also elected to Parliament for the recently enfranchised borough of Amersham. Due to the number of Clarkes sitting in the House, the only committee appointment that can certainly be ascribed to him was to investigate the abuse of purveyors, a long-standing Buckinghamshire grievance (25 May 1626).
Clarke died on 18 Oct. 1626, four days after making his will, and was buried in Hitcham church.
